adult time course at each voxel (Cantlon & Li 2013, Moraczewski et al 2018, Richardson et al 2018). Intersubject approaches comprise a unique hybrid insofar as they are model-free, but depend on time-locked signal changes. Studies to the left highlight the combined use of multiple types of analyses on the same data set, and asterisks denote pediatric studies. Spectrum of analytic approaches to movie-watching data, with examples. Methods for these analyses are in Supplementary Materials. All data are from the publicly available Healthy Brain Network biobank (PI: Michael Milham, Alexander et al 2017). E) The best-fit lines show the striking effect of age on head motion for rest, which was somewhat diminished during the movie. D) When binned by age, mean head motion advantage was greatest for children under age 10 years. Most of the red dots are below the diagonal, indicating that the 50 worst subjects during rest were not also the worst during the movie. C) The 50 subjects with the highest mean framewise displacement (FD) during rest are labeled in red.
#MPEG4 BIG HERO SIX DOWNLOAD MOVIE#
B) For the group as a whole, the movie significantly improved head motion relative to rest (p<0.0001). A) Sample age distribution shows skew towards younger subjects. Two 5-minute rest runs were concatenated to match the duration of the movie run (Despicable Me (DM)). Pediatric head motion in movies and rest (N=356, mean age 10.42 years ± 3.4), from a help-seeking community sample. Future directions and cautionary notes highlight the potential and the limitations of using movies to study FC in pediatric populations. Converging evidence suggests an enhanced ability to identify brain-behavior correlations in children when using movie-watching data relative to both resting state and conventional tasks. Emerging themes from movie-watching studies are discussed, including an emphasis on intersubject correlations, developmental changes in network interactions under complex naturalistic conditions, and dynamic age-related changes in both sensory and higher-order network FC even in narrow age ranges. This review highlights the advantages and challenges of using movies for developmental neuroimaging and explores some of the methodological issues involved in designing pediatric studies with movies. Using naturalistic paradigms such as movies has also provided analytic flexibility for these developmental studies that extends beyond conventional resting state approaches. The use of movie-watching as an acquisition state for functional connectivity (FC) MRI has recently enabled multiple groups to obtain rich data sets in younger children with both substantial sample sizes and scan durations.
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